The action of Rauwolfia serpentina alkaloid on the blood vessel

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منابع مشابه

A Priliminary Note on the Pharmacological Study on Reserpine a New Alkaloid Isolated from Rauwolfia Serpentina

Rauwolfia serpentina, Benth, commonly known as Insanity herb has been used for a long time in Ayurvedic System of Indian Medicine. It has been highly advocated as a general sedative in sleeplessness, anxiety neurosia and hysteria and in the treatment of epilepsy, maniacal and acute insanity. Siddiqui & Siddiqui (19321935) studied the chemistry of some of the active principles extracted from the...

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Rauwolfia serpentina in the treatment of high blood-pressure.

The root of the Rauwolfia serpentina Benth (N. 0. Apocyanaciae) has been in use in India for hundreds of years for a host of unrelated ailments. Since 1949, after the English publication of a clinical report by the author on Rauwolfia serpentina therapy in fifty cases of essential hyperten-sion, the plant has gained universal acclamation as a useful therapeutic weapon in high blood pressure sta...

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Cytotoxicity of the indole alkaloid reserpine from Rauwolfia serpentina against drug-resistant tumor cells.

BACKGROUND The antihypertensive reserpine is an indole alkaloid from Rauwolfia serpentina and exerts also profound activity against cancer cells in vitro and in vivo. The present investigation was undertaken to investigate possible modes of action to explain its activity toward drug-resistant tumor cells. MATERIAL AND METHODS Sensitive and drug-resistant tumor cell lines overexpressing P-glyc...

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Pharmacognostical Profiling on the Root of Rauwolfia Serpentina

Each medicinal plant and the specific plant part used as crude drug material contain active or major chemical constituents with a characteristic profile that can be used for chemical quality control and quality assurance. So the increasing demand for herbal medicines has inevitably led to maintaining the quality and purity of herbal raw materials and finished products. WHO acknowledged that Pha...

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Rauwolfia Serpentina in Essential Hypertension

jHauwolfia serpentina has been known as a medicinal plant in India for a long time but its use in the treatment of hypertension is of comparatively recent origin. The dried root contains 1 per cent of total alkaloids besides resin, starch, potassium carbonate, phosphate, silicate and traces of iron and manganese (Sen and Bose, 1931). Siddiqui and Siddiqui (1931) found two groups of alkaloids an...

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ژورنال

عنوان ژورنال: Folia Pharmacologica Japonica

سال: 1957

ISSN: 0015-5691,1347-8397

DOI: 10.1254/fpj.53.1075